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RNA sequencing (RNA-seq) and data analysis MKN45 cells were inoculated into large dishes at 7 10 4 cells/well, and 4 nM concentration of 1D228 was added after 12 h

It is also used for heart disease, premenstrual syndrome (PMS), depression, morning sickness, Alzheimer disease, menstrual cramps, diabetes, and many other conditions, but there is no good scientific evidence to support many of these other uses

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All AEs will be followed up until resolution or stabilisation as judged by gynaecologist or paediatrician (site investigator) and the principal investigator

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