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The acylcarnitine crosses the inner mitochondrial membrane, where the fatty acid is transferred back to CoA for beta-oxidation

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The food and diet supplement industry has in past made claims that later did not hold up to scientific scrutiny

We also uncovered an unexpected role for CoQ in the transcriptional regulation of pivotal thermogenic genes like UCP1, affecting uncoupled respiration and leading to a rise in the inner mitochondrial membrane potential and a decline in ADP/ATP ratios (Chang et al, 2022)