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Comprehensive analysis of the gene encoding filaggrin uncovers prevalent and rare mutations in ichthyosis vulgaris and atopic eczema

However, the appearance of the skin can be distressing, particularly if the face or the hands are affected

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Although the exact etiology of PCOS remains unclear evidence points toward a strong heritable component possibly modulated by gestational environmental exposures and lifestyle factors [12]

Patients may consider a medical evaluation when excess skin contributes to: When these symptoms are present, panniculectomy surgery may be discussed as a functional procedure to remove excess lower abdominal skin