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In support of a key role of NF-B in the regulation of astrocyte homeostasis and the pre-disposition to detrimental post-traumatic responses, recent studies showed that transcriptional changes underlying astrocyte reactivity can be highly heterogeneous in different neuropathological conditions and depend on context-specific transcription factor crosstalk 9,17

Discussion Elevated antioxidant gene expression in hooded seal neurons We here extend the work of Gener et al

In the second strategy, called gene trapping, researchers again manipulate a gene in an ES cell