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Mol Pharmacol

However, deficiencies are common, particularly in individuals with: Limited intake of B12-rich foods (vegetarians, vegans)

Patients with neurological symptoms require more intensive treatment with alternate-day injections until improvement plateaus, and may need more frequent maintenance dosing

Adequate B12 levels protect against nerve damage, numbness, and tingling that can become irreversible if left untreated

Clinical obesity trials tested 12-week cycles
