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Gabrieli 6 , Teddy Wu 7 , Leonard Yeo 1 1 National University Hospital (NUH), Singapore, Singapore, 2 Chang Gung Memorial Hospital, Linkou Medical Center, Taiwan, 3 University Hospital Knappschaftskrankenhaus Bochum GmbH, Bochum, Germany, 4 Martin-Luther-University Halle Wittenberg, Halle (Saale), Germany, 5 Nuffield Department of Population Health (NDPH), University of Oxford, Oxford, United Kingdom, 6 Padova University Hospital, Padova, Italy, 7 New Zealand Brain Research Institute, Christchurch, New Zealand Background and Aims: Mechanical thrombectomy is the standard of care in the treatment of acute ischemic stroke with large vessel occlusion (LVO)

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Animal data provides biological plausibility and mechanistic insights but cannot guarantee human efficacy

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