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The German BfArM and equivalent agencies (ANSM in France, AEMPS in Spain, AIFA in Italy, URPL in Poland) treat unauthorized human use of these compounds as outside the scope of the marketing authorization regime entirely

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Moreover, some clinical trials of the combination of DSF and copper have been completed (NCT00742911 and NCT03034135) or are in progress (NCT04265274, NCT03714555, NCT03363659, and NCT02715609), providing a potential strategy for tumor therapy

doi: 10.1038/s41598-019-53964-y