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We eventually succeeded in creating a model that had between 12- to 20- fold higher 5-OP levels, substantially higher folds than observed in mammalian system

However, the diameter ranges with differences in the frequency of pain are not clear, since painful insertions decreasing from 63% to 31% in the 2332 G range have been reported [16] whereas other authors found no differences in injection pain when comparing needles in narrower ranges, such as 2630 G [17, 18]

2020 Jan 3;3(1):e1919274

We would also like to thank NIH National Center for Complementary and Alternative Medicine, the Bernard Osher Foundation, and Bastyr University Research Institute for providing funding for the study authors to conduct this study