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For those considering Cerebrolysin, key limitations include: no prevention trials have been conducted (all studies in existing disease), optimal dosing remains uncertain (higher doses may actually be less effective), batch-to-batch variability in peptide content, and the inconvenience of repeated IV infusion cycles

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We pretreated HepG2 cells with diamide, a well-established protein S -glutathionylation induction agent, for 2 h, followed by TNF stimulation

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Brooks AJ, Dai W, O'Mara ML, Abankwa D, Chhabra Y, Pelekanos RA, Gardon O, Tunny KA, Blucher KM, Morton CJ, Parker MW, Sierecki E, Gambin Y, Gomez GA, Alexandrov K, Wilson IA, Doxastakis M, Mark AE, Waters MJ

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Feb 2017;31:6-16

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