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Perifollicular capillaries regress as the follicle shrinks, starving remaining cells of oxygen and nutrients

doi:10.1038/jhg.2012.113 Yan L, Zhao L, Long Y, Zou P, Ji G, Gu A, Zhao P (2012) Association of the maternal MTHFR C677T polymorphism with susceptibility to neural tube defects in offsprings: evidence from 25 case-control studies

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Conversely, other studies revealed that the decreased survival of cancer patients is associated with the suppressed expression of GPx2, confirming the tumor-suppressive function of GPx2 (Ren et al