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Under physiological conditions, Cys-SSH and GSSH are major products, and even though Cys-SS n H and GSS n H are produced, they may be immediately reduced by cysteine and GSH

These studies are particularly encouraging given the great potential of immunotherapy in anti-cancer treatment, and suggest that high-dose VitC may be a promising combination strategy to convert cold tumours into hot tumours, further widening the therapeutic scope of immunotherapy

Rossi Fanelli, Sapienza University of Rome and Istituto Pasteur-Fondazione Cenci Bolognetti, P