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It's worth noting that metformin, commonly used for diabetes, is actually associated with reduced B12 levels rather than elevation

These safety findings were crucial for advancing it into efficacy trials focused on weight loss
They can help in the management of neurological ailments such as diabetic neuropathy and may support better sleep patterns, mood enhancement, and cognitive function due to its role in synthesizing neurotransmitters

MHRA guidance (2022) recommends B12 monitoring for patients on long-term metformin therapy

O.SchwarzenbergerP