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doi: 10.1371/journal.pone.0062934
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Joint discomfort associated with B12 supplementation is uncommon and not listed amongst the recognised adverse effects in the Summary of Product Characteristics (SmPC) for licensed B12 preparations or in the British National Formulary (BNF)
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Start with a Lower Dosage But perhaps the most important thing we can recommend is starting at a low dosage and slowly ramping up as your body adjusts to the medication
