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They may differ from commercially available or FDA-approved drugs in efficacy, safety, risk, and side-effect profiles

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It also indicates that hypomagnesemia may occur within 1 year of PPI therapy initiation and can have serious clinical consequences[227] At present the mechanism of the PPI-induced low magnesium levels is not known

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The downstream effects of NNMT inhibition by 5-amino-1MQ create a cascade of beneficial metabolic changes at the cellular level

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