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In patients with endometriosis, progesterone resistance is observed, possibly related to a decrease in PRB levels [86], which tends to inactivate progesterone target genes, leading to inflammation and deficient estrogen metabolism [87]

Accessed 06/17/25, Vera J

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Although the mechanisms are unclear, multidrug resistance protein 1 (otherwise known as ABCC1) has been reported to preferably export GSSG under conditions of high intracellular GSSG (33, 34)

However, while ROS are essential in pathogen clearance, excessive or prolonged production can result in tissue damage