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Some basic functions GAGs Structural component of the extracellular matrix Cell signalling and adhesion Facilitate hydration of tissues Act as lubricants and shock absorbers to support compressibility of cartilage Transport/movement of nutrients and wastes Tissue formation Cell migration and movement Many roads all lead to SULFATE It has already been stated that the body is required to oxidise all other forms of sulfur into the end product sulfate - so that it can be utilised in the sulfation pathway