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21 This enzyme is responsible for reducing glutathione disulfide (GSSG) to its sulfhydryl form, known as glutathione (GSH), a potent endogenous antioxidant agent

& Hickey, W

[13] Chloramphenicol has been shown to blunt reticulocyte response to cyanocobalamin, while ethanol, colchicine, and nitrous oxide interfere with cobalamin metabolism or utilization, each warranting clinician awareness when evaluating suboptimal treatment outcomes

The tumor promoter arsenite stimulates AP-1 activity by inhibiting a JNK phosphatase

[19] [20] More recently researchers have discovered a feline family that exhibits deficiencies in -glucuronidase activity