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Dihexa's synaptogenic effects require activation of the c-Met receptor, as demonstrated by experiments using c-Met-specific short hairpin RNA (shRNA) which completely abolished Dihexa's capacity to induce spine formation

Nature 400 , 269271 (1999)

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Participants received no financial compensation for taking part in this study

When symptoms are present, they usually relate to the underlying condition causing the elevation rather than the high B12 itself