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The association of SOD and HsCRP with the efficacy of sulforaphane in schizophrenia patients with residual negative symptoms
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Superoxide anion radicals (O2 ) can cause injury directly and can be converted into more damaging oxidant species such as hydroxyl radical (OH ) and hypochlorous acid (HOCl).37 Of the two, OH has been demonstrated as the key reactive oxygen species to cause pulmonary edema during acute lung injury.38 Hypoxemia secondary to Adult Respiratory Distress Syndrome (ARDS) and pulmonary edema may occur during COVID-19 infection.39 Besides causing tissue injury, ROS can also activate the NF-kB pathway to amplify inflammation through upregulation of expression of multiple genes, such as IL-6, TNF-, and chemokines
doi: 10.1038/s42003-024-06704-6 44 ShiKLvYZhaoCZengHWangYLiuYet al
Various versions of HT have been reported with various HLA alleles, including DR3, DR5, DQ7, DQB1*03, DQw7, or the DRB1*04-DQB1*0301 haplotype
