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Meakin, P.J., et al., Susceptibility of Nrf2-null mice to steatohepatitis and cirrhosis upon consumption of a high-fat diet is associated with oxidative stress, perturbation of the unfolded protein response, and disturbance in the expression of metabolic enzymes but not with insulin resistance

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Panax ginseng modulates the CD4 + T cells and CD11b + macrophages infiltration into the spinal cord and reduces demyelination and axonal damages other than to reduce the pro-inflammatory factors production such as IFN-, IL-17, and TNF- in both mice models of primary progressive and relapsing-remitting MS ( Lee et al