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In addition, compelling evidence suggests that DNA damage response (DDR) signaling is a predominant mechanism associated with the build-up of DNA damage, aging, and cell senescence (Malaquin et al., 2015)

J Thorac Cardiovasc Surg 150(3):613-619.e2, 2015

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The resulting CUR-DG4.5 complexes exhibited good biocompatibility, improved cellular uptake, antioxidant activity evidenced by DPPH radical scavenging, protection against HO-induced oxidative stress, and effective interference with -synuclein aggregation (117) (Figure 2)