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(1998) observed that zinc supplementation for healthy subjects aged 2050 years reduced the concentration levels of MDA (malondialdehyde), 4-hydroxy alkenals (HAE), and 8-hydroxy deoxyguanine, which are oxidative stress markers in plasma [109]

Massive inflammatory reaction is observed when there is a dysregulated ratio of pro-inflammatory to anti-inflammatory cytokines (Figure 1 and Figure 2) [6,27]