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Aplastic Anemia Various cases of aplastic anemia associated with CD have been described in the literature, both in pediatric age and in adulthood [123,124,125,126,127,128]

In addition, other tissue metabolism disorders also occur, such as nervous system damage

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Treatment of persistent sleep-wake schedule disorders in adolescents with methylcobalamin (vitamin B12) The improvement of the sleep-wake rhythm disorders appeared immediately after the administration of high doses (3,000 micrograms/day) of methylcobalamin