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27 Another study compared a combination oral supplement that included 600 mg/d ALA along with gamma-linolenic acid to a vitamin supplement containing vitamins B1, B6, and B12 over 3 months in 112 patients with moderate to severe CTS.28 Researchers found similar results, with significant pain reduction and improved function in the ALA treatment group with only slightly improved pain reduction in the vitamin B group but with worsened function

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A single course of phenobarbital for alcohol withdrawal (10-20 mg/kg cumulative dose within a short period of time) is unlikely to cause substantial enzyme induction

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If from the Department of Public Health and Preventive Medicine (DPHPM), make sure it has gone through the Research and Service Committee (RSC) for review prior to IRB submission, and that all suggestions have been incorporated in the document or justified before submitting to the IRB