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The present review discusses applications of epigenetic alterations affecting GSTP1 in cancer medicine used alone or in combination with other biomarkers for cancer detection and diagnosis as well as for future targeted preventive and therapeutic interventions including by dietary agents

Conversely, excessive intake can lead to acute toxicity presenting with nausea and increased intracranial pressure, or chronic toxicity characterized by alopecia, hepatomegaly, and teratogenesis

doi: 10.1038/s41590-021-00962-w 241 SartoriusR.TrovatoM.MancoR.DApiceL.De BerardinisP

[DOI] [PMC free article] [PubMed] [Google Scholar] 46.Jagt D.L.V., Hunsaker L.A

We observed behavioral changes of rats such as restlessness, drowsiness, piloerection, writhing, convulsion and mortality if any for 8 h at an interval of one hour and then for the next 48 h at an interval of 4 h