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If unexplained

For instance, in one 1960s study of intravenous NAD+ for addiction, patients who received a fast IV drip experienced immediate headache and shortness of breath, whereas those given the same dose at a slower drip rate (under ~35 drops/min) had no distress

Atherosclerosis 172: 229-386

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Drug-induced malabsorption: Long-term medications like metformin or proton-pump inhibitors can reduce B12 absorption
