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More recently, a mitochondrial targeted antioxidant Mito-Tempo was reported to protect against AILI even at 3 h post-treatment of APAP compared with NAC alone, suggesting it as a potential therapeutic option for patients at late phase in APAP poisoning [29]
These mice also have reduced inhibitory serine-73 phosphorylation of PPAR, resulting in the enhancement of PPAR signaling in the liver [15]
& Gebhard, C
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