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Funding This research did not receive any specific grant from funding agencies in the public, commercial or not for profit sectors

While our bodies produce it naturally, levels drop with stress, age, and pollution

Yan Chen, [email protected] These authors have contributed equally to this work This article was submitted to Cellular Biochemistry, a section of the journal Frontiers in Cell and Developmental Biology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Animal studies report biological activity after oral administration, especially in gastrointestinal models, which suggests potential local effectiveness

Genome Res (2006) 16(6):693701.10.1101/gr.5120106 284 CaoGLuHFengJShuJZhengDHouY