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Hyperlipidemia is a prevalent source of oxidative stress that has been shown to increase red cell fragility and induce hemolysis, though the extent to which it may induce chronic low-grade intravascular hemolysis in a G6PD-d model is uncertain 58,59

[DOI] [PMC free article] [PubMed] [Google Scholar] 44.Scremin O.U., Jenden D.J

Another logical strategy to overcome leptin resistance is to manipulate leptin-regulated pathways distal to the first-order neuron, which is the melanocortin pathway

doi: 10.1038/s41467-022-29018-9
