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Incretin receptor agonists, including tirzepatide, may potentially increase the risk of thyroid C-cell tumors based on findings in animal studies

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HbA1c reductions of 1.5-2.5 percentage points are common

What that means isnt always straightforward: In the Swiss study mentioned above, nearly three-quarters of primary-care docs surveyed reported using a multi-step approach (and not always the same one) when testing for B12 deficiencya practice that Miller says improves the odds of an accurate diagnosis since serum B12 levels alone dont always accurately identify a deficiency

This is largely in view of the high cost savings, ease of administration and reduced pain and injection-associated injury (Wentworth and Copland, 2018)