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Description
Activation of the TMAO-induced endothelial NLRP3 inflammasome was reduced by a mitochondrial ROS scavenger or SIRT3 overexpression in human umbilical vein endothelial cells (HUVECs), which suggested that the activation was mediated in part by inhibition of the SIRT3-SOD2-mtROS signaling pathway (Zhou et al., 2010

Li Y, Zhang H, Yu C, et al

DNA Repair 7 , 11101120 (2008)

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doi: 10.1371/journal.pone.0213981
