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This classical anti-mitotic drug binds soluble tubulin at colchicine site between - and -subunits, thus irreversibly forming tubulin-colchicine complexes, which induce many conformational changes in tubulin, disrupt further microtubule polymerization, and finally block mitosis at metaphase and induce cell death 50

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This treatment aids in achieving a more even skin tone without significant side effects or downtime

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