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This limitation matters because repeated-dose toxicity guidelines normally expect systematic clinical observations, body weight tracking, hematology, clinical chemistry, organ weights, and histopathological examination under a defined study design

Role of oxidative stress in the pathogenesis of nonalcoholic steatohepatitis

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The researchers observed that senior cats exhibited significantly reduced levels of erythrocyte and whole blood glutathione (GSH), along with elevated oxidative stress markers compared to younger counterparts

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