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A microarray analysis performed on non-malignant human pancreatic cells overexpressing Gli1 (Hedgehog transcription factor) identified NNMT as one of the 26 potential target genes of the Hedgehog signaling pathway [81]

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Current Pharmaceutical Design , 2020 Injecting Far from the Injury Site (When Localized Healing Is Needed) If you're recovering from a joint, tendon, or ligament injury , injecting into the abdomen wont target the injured tissue as efficiently

And the early growth response 1 (egr-1) gene expression pattern, originally identified in skin wound healing, also appears in muscle and tendon repair work, suggesting a shared transcriptional response

But unless the mechanisms are complementary rather than redundant, stacking adds cost and complexity without proportional benefit