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A near two-fold increase in the AMPA-mediated currents was measured following treatment with 10-12 M Nlel-AngTV and Dihexa (Figure 6A and B)

To obtain a receptorG protein complex with good homogeneity and stability, we used the NanoBiT tethering strategy, in which the C-terminus of rat G 1 was linked to the HiBiT subunit with a 15-amino acid polypeptide (GSSGGGGSGGGGSSG) linker and the C-termini of CCK1R and CCK2R were directly attached to LgBiT subunit followed by a TEV protease cleavage site and a double MBP-tag

Journal of Nutrition for the Elderly