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The timeline for expected therapeutic response may vary based on the condition being treated and individual patient factors

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Community reports suggest sleep disruption is less common with oral dosing, though no controlled comparison exists

At the late stage, increased lipophagy releases PUFAs that serve as substrates for lipid peroxidation, whereas the knockdown of RAB7A or PGRMC1 inhibits lipophagy-induced ferroptosis [210, 211]