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However, the translational gap between the in vitro efficacy and the in vivo performance of many bioactive compounds (BACs) remains a major bottleneck in the development of efficacious nutraceutical products (1, 2)

Pietragalla A

This method may also be useful for children or individuals who have trouble swallowing pills

In addition, in a randomized double-blind casecontrol study on whether VD3 supplementation inhibited the progression of PD, VD3 significantly prevented the deterioration of the Hoehn and Yahr scale in patients with PD compared to placebo controls (90)

This underscores the urgency to advance PD therapeutic approaches