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These data indicate that celastrol inhibits pro-apoptotic JNK signaling in neomycin-exposed utricles

Comparison of kidney homogenates from wild-type and GGT-null mice demonstrated that both GGT and GGT-rel cleave LTC 4 to LTD 4 (Carter et al., 1994, Han et al., 2002)

Enzyme replacement treatment (ERT) with recombinant human -Gal A decreased the Gb3 accumulation and oxidative stress, which resulted in amelioration of the deformed cellular structure of the GLA-mutant kidney organoids

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Therefore, if a BPC-157-treated culture shows increased FAK Tyr397 phosphorylation relative to vehicle control, the cautious interpretation is that BPC-157 is associated with a migration-related signaling state in that specific model