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I've never taken 'expiry' / 'best before' / 'use by' dates totally to be adhered to, except in certain circumstances

doi: 10.1016/S1535-6108(03)00050-3 18 YangWSStockwellBR

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FICZ, an endogenous AhR ligand, increases regulatory T cells, reduces proinflammatory T cell responses, and ameliorates fibrosis in BLM-induced models [115]

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