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Another study also supported -Syn as a potential PD biomarker (Elhadi et al., 2019)

Emerging evidence underscores the pivotal role of mitophagy in the pathogenesis of conditions such as PD, Alzheimers disease (AD), Huntingtons disease (HD), and amyotrophic lateral sclerosis (ALS)

doi: 10.2169/internalmedicine.43.649, PMID: [DOI] [PubMed] [Google Scholar] 248.Shahab MH, Saifullah Khan S

Notably, ferroptosis-resistant FLS exhibited a greater amount of tumor necrosis factor (TNF)-related transcriptome
This indicates higher water solubility, which could also reduce or prevent protein aggregation and denaturation of the bioconjugates 47,48