disulfiram and glutathione in liver diseases: a double-edged sword | Naunyn-Schmiedeberg's Archives of Pharmacology A Class of Disulfide Compounds

Description

We examined the clinical studies on phytochemistry and pharmacological application of BME

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It has been proved that BaP reduced genome-wide DNA methylation, and activated proto-oncogene by hypomethylation in the promoter region, but silenced tumor suppressor genes by promoter hypermethylation, resulting in cancer initiation and progression