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Reported EC50 values include: GIP receptor: Approximately 0.064 nM GLP-1 receptor: Approximately 0.775 nM Glucagon receptor: Approximately 5.79 nM In research models, retatrutide activates several metabolic pathways

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Cotillard, A

This is not due to changes in cholesterol or SM levels (which were reduced in these rafts) but to a decrease in the unsaturation of fatty acids
