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In parallel, AGE can reverse neuronal loss in the CA1 and CA2 regions of the hippocampus, increase the activity of antioxidant enzymes, including SOD and glutathione peroxidase (GP), as well as decrease the malondialdehyde (MDA) level in the A-exposed rat brain homogenate

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3 were initially assigned a role in maintaining GSH homeostasis ( Arabidopsis , mirroring the function of mammalian CHAC2 (Vernoux et al., 2000)

Il semblerait notamment exister un lien avec lactivit de la tlomrase, une enzyme qui a une influence sur la survie cellulaire en prservant les tlomres

Overoxidation of the selenoprotein would inactivate that protein, and thus prevent it from carrying out its oxidative functions