oxidized glutathione definition Chemical structures of (GSH) and glutathione (GSSG) Frontiers | Glutathione: A Samsonian

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Tau-mediated iron export prevents ferroptotic damage after ischemic stroke

T.DarinK

however, it has also been established that 2-oxo acid dehydrogenases, particularly pyruvate dehydrogenase complex (PDC) and 2-oxoglutarate dehydrogenase complex (OGDHC, also known as ketoglutarate dehydrogenase), are oxidant generators under permissive conditions and are themselves subject to redox modifications [4-9]

ROS seem to be the key factors in brain aging processes and mitochondrial respiration with ROS production significantly contributes to functional changes in brain during aging