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The mitochondrial transcription factor A (TFAM) mRNA carried by MSC-EVs can alleviate mitochondrial damage and inflammation by stabilizing mtDNA (Zhao et al., 2021)

oxidized glutathione is used as a measure of cellular toxicity

Glutathione is a natural antioxidant that is produced in the body, but levels can be depleted by factors such as stress, toxins, and aging

Cell 180 , 296310.e18 (2020)

Why KPV may succeed where other treatments struggle Remember that 40 percent non-response rate with anti-TNF therapy
