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Novel model system for a severely compromised oxidative stress response"
British Journal of Nutrition , 110 , 11781187
a tissue specific promoter is only active in specific types of differentiated cells/tissues
Depletion of GSH due to intensified oxidative stress or the action of inhibitors significantly reduces the ability of GPX4 to counteract lipid peroxidation, leading to increased lipid peroxides and subsequent ferroptosis (151)
While all types of chelation therapy can be effective, IV chelation has the highest bioavailability (100%) because its administered directly into the bloodstream
