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5.2 Disorders of mitochondrial long-chain fatty acid oxidation 5.2.1 Very long-chain acyl-CoA dehydrogenase (VLCAD) deficiency Clinical presentation Patients diagnosed with VLCAD deficiency (OMIM 201475) can suffer from hepatic, cardiac and muscular symptoms that can appear in infancy, but also later during adolescence or adulthood

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This process is vital for maintaining energy levels, especially during prolonged physical activity

Ion Channel Disturbances in Migraine Headache: Exploring the Potential Role of the Kynurenine System in the Context of the Trigeminovascular System