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Description
RM-718 RM-718 is a cyclic heptapeptide developed by Rhythm Pharmaceuticals using setmelanotide as a template, with a focus on increasing MC4R potency and selectivity while limiting activity on MC1R to reduce skin pigmentation effects for once-weekly injection ( Figure 2 ) (130)

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Clinical studies results
y cols.: "Epithelial and mesenchymal hamartomatous changes in a mature port-wine stain: Morphologic evidence for a multiple germ layer field defect"

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