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The following is the typical dosing schedule for weeks 5-16: Weeks 5-8: 0.5 mg (semaglutide) / 0.5 mcg (vitamin B12) once weekly Weeks 9-12: 1.0 mg (semaglutide) / 0.5 mcg (Vitamin B12) once weekly Weeks 13-16: 1.7 mg (semaglutide) / 0.5 mcg (Vitamin B12) once weekly Weeks 17 onwards: 2.5 mg (semaglutide) / 0.5 mcg (Vitamin B12) once weekly, if further weight loss is required

Therefore, clearing senescent cells is crucial for delaying the aging process (Su et al., 2021)

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One month was chosen as the length of time for the study for two reasons

doi: 10.2741/3428