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Evergreening Tactics and the Orange Book as an IP Roadmap Evergreening is the practice of layering new patents onto an approved drug product to extend the effective period of market exclusivity beyond the original composition-of-matter (COM) patent
Inhaled NAC can do this, decreasing the mucus and helping to alleviate symptoms

After such analyses, the FDA approved a supplemental license application for reintroducing natalizumab as monotherapy treatment for relapsing forms of multiple sclerosis in 2006
